Oxandrolone 5mg is an anabolic steroid.
Once inside the cell nucleus, activates the genetic apparatus of cells, which leads to increased synthesis of DNA, RNA and structural proteins, activates enzymes of tissue respiration chain and enhancing tissue respiration, oxidative phosphorylation, ATP synthesis and accumulation of makroergov inside the cell.
Stimulates anabolic and inhibits catabolic processes induced by glucocorticoids.
Leads to increase muscle mass, decrease fat deposits, improves trophic tissues, promotes calcium deposits in the bones. Shows low androgenic activity.
Disorders of protein synthesis, cachexia different origin; trauma, extensive burns, after infectious diseases and radiation; muscular dystrophy, osteoporosis, negative nitrogen balance corticosteroid therapy, Hypo – and aplastic anemia.
METHOD OF APPLICATION AND DOSES
Adults: the dosage is individual. The usual dose for adults is 2.5-20 mg per day, divided into 2-4 reception.
Children: recommended dose is ≤ 0.1 mg/kg/day.
The duration of treatment is usually 2-4 weeks. If necessary, the treatment can be repeated after 1-2 months.
Women — virilization symptoms, acne, disorders of the menstrual cycle.
Men: in prepubertal period — virilization symptoms, acne, slowing or stopping growth (calcification of epiphyseal growth zones tubular bones); postpubertatne period-gynecomastia, priapism, inhibition of spermatogenesis.
Men and women — progression of atherosclerosis, peripheral edema, impaired liver function, changes in the leucocyte count, pain in the long tubular bones.
Hypersensitivity to the drug, prostate cancer, breast cancer in men carcinoma of the breast in women with hypercalcemia, ischemic heart disease, severe atherosclerosis, hepatic and renal failure, acute and chronic prostatitis, pregnancy, breast-feeding.
PRECAUTIONS AND APPLICATION FEATURES
When the first signs of virilization in women (thickening of the voice, hirsutism, acne, clitoromegaly), the intake should be stopped to avoid irreversible changes. Periodically check the level of lipidemia and hypercholesterolemia.
Children drug should be appointed an experienced specialist to avoid premature epiphyseal ossification of the bones.
INTERACTION WITH OTHER MEDICATIONS
Enhances the action of anticoagulants, antiplatelet agents, and hypoglycemic agents, as well as side effects gepatotoksicnah drugs.