Deca-Durabolin® is a trademark of Organon, which is used for the injectable steroid nandrolone decanoate. This drug first appeared as a drug in 1962. This steroid has a very long effect, as a complex decanoate ester provides a slow release of steroid in the body from 3 to 4 weeks. However, further studies indicate that the rate of release of the steroid into the body after a single injection are such that a significant concentration of drug in the body is maintained only for one or two weeks. If to take into account the fact that the drug accumulates after multiple injections, it becomes clear that in this case the effect of the medication will be longer. Figure 1 (page 71) shows the dynamics of release in the body 200 mg of the steroid after 1 injection. As seen in the chart by the end of 2 weeks, the concentration of drug is reduced to almost 0.
Figure 1. Pharmokinetics injection of 200 mg of Nandrolone Decanoate.
World famous Deca-Durabolin (Nandrolone decanoate) 1ml, 100mg/ml is one of the most widely used anabolic steroids. This stems from the fact that he has many positive characteristics. The structure of the nandrolone is very similar to testosterone, only he doesn’t have a carbon atom at the 19th position (hence its other name 19-nortestosterone). Such structure of a steroid relieve him of some androgenic characteristics or do they have it weaker than that of testosterone. Interesting is the fact that nandrolone will not break down to active metabolites in the tissues is the site of action of androgens. You may remember that this is one of the problems associated with testosterone. Although nandrolone undergoes disintegration due to the same enzyme (5-alpha reductase) which convert testosterone to DHT, in the case of nandrolone, it becomes dihydroindole. This product is somewhat weaker than nandrolone, and almost has no unwanted androgenic effects. Only sometimes there are strong occurrences of oily skin, acne, hair growth on body and face or loss of hair. Of course, such manifestations are possible while taking any other steroid, but with nandrolone, it may be caused by a high dosage.
Furthermore, nandrolone shows a very lower tendency for estrogen conversion. For comparison, this rate is about 20% of the speed of transformations with testosterone. Perhaps it is because while the liver converts nandrolone to estradiol, in other tissues, where the process of aromatization of steroids, for example, in adipose tissue, nandrolone is not amenable to this process. Therefore, this drug rarely causes side effects action of estrogen. So when taking Deca, you do not need to take any antiestrogens only very sensitive patients may encounter gynecomastia. At the same time, the delay fluid in the body is also rare, only in case of high dosages. The additional intake of Proviron® and/or Nolvadex® will help you to avoid any manifestations of the aforementioned phenomena. Clearly Deca is one of the safest ways among steroids. Many in fact consider it one of the best steroids that can be used by people. It should also be noted the fact that in HIV studies, Deca has proven to be a very effective means of accumulation of mass in slim patients, and has proved very beneficial remedy for the immune system.
It should also be noted that nandrolone has the same activity in the body as a progestin. Although progesterone is a C-19 steroid, removal of this group from 19-norprogesterone turns it into a hormone with greater binding capacity with the appropriate receptor. Many 19-nor anabolic steroids have the same feature and also show some activity against progesterone receptors. All this leads to their activity in the body, resembling the activity of the progestin, and may intensify related side effects. Side effects of progesterone is very similar to the same symptoms associated with estrogen. It’s slower production of testosterone, increased fat storage and possibly gynecomastia. Many believe the progestin activity, by taking Deca , significantly contributes to suppression of testosterone synthesis, which is also associated with a slight ability Deca to estrogen conversion.
Deca is not considered a tool for the fast accumulation of mass. The effect of building muscle is very noticeable in this preparation, but not pronounced. But “slow” start and mild properties of this steroid therefore make it very suitable for long cycles. Taking Deca, you will gain half the weight you could gain, taking the same amount of testosterone. It makes most sense to follow a cycle of 8-12 weeks, gradually gaining ground. Since Deca remains active in the body for a long time, usually enough to do 1 injection per week. The usual dosage for men is 200-600 mg. more specifically, it is assumed that the optimal effect of Deca possible at the rate of 2 mg per 1 pound of patient weight (1 pound= 373,2 g) per week. Deca is also popular among female bodybuilders. Of course, they take a much smaller amount of the drug, on average, about 50 mg per week. Although the drug is androgenic, women are occasionally confronted with virilization symptoms during his admission. If you are experiencing these symptoms, it is best to go to the Durabolin® as a drug less long-acting. This drug stays active for only a few days and greatly reduces the androgenic symptoms, if necessary.
As mentioned earlier, endogenous testosterone levels can vary while taking Deca-Durabolin®, especially after long cycles. It is therefore advisable to take additional medications at the end of each cycle. Most often it is the antiestrogens Clomid® or Nolvadex®, which take a few weeks. Both the drug is well affect the production of testosterone, though to achieve good results will take some time. Injections of Human Gonadotropin (CGH) will also help to rapidly restore the normal ability of the testes to respond to a minor release of gonadotropin. For this you can also apply 3 injections at 2500-5000 int. units with a period of 5 days. Then continue to take the antiestrogen for another few weeks in order to stabilize the production of testosterone. Don’t forget that additional funds are beginning to take after discontinued intake of Deca in a few weeks, and not just in the first week after the last injection. Deca stays active enough for some time so the ancillary drugs will not be able to Express themselves optimally, when the steroid is still going to get into the blood.
The main drawback of this drug is that if it is to participate in the competition, it will be detectable in your blood for years or more after the end of the reception. This is due primarily to the release form. As mentioned above, the compounds of the esters have a high ability to stay permanently in fatty tissue. While we can calculate the period of time that is required in order to a certain dose of drug in the blood after entering the body, while we cannot be completely sure that at this point the steroid were subjected to disintegration. The small amounts of drug may remain in fatty tissue, especially after long cycles of “heavy” steroids. Some quantity of nandrolone decanoate do sometimes continues to enter the bloodstream for many months after the end of the reception. This process may be further aggravated when dieting and preparing for the performance, as during this period, the fat reserves in the body are being actively depleted and thereby frees up additional amounts of steroids. This may explain the unexpected positive reaction to the steroid during inspections. The fact that nandrolone has been excluded from the group of drugs that can make athletes passing a test for doping, possibly associated with its popularity and, consequently, that it is easy to detect during analyses. The same characteristics and have other long-acting steroids like Equipose®, Parabolan and Primobolan®.
On the other hand we found that the use of oral nandrolone predecessor norandrostenedione and norandrostenediol, much easier for athletes than injections of nandrolone as it saves them from positive test results. Recent studies in France confirm these data. During these studies it became clear that the tracks of the decay products of nandrolone, norandrosterone and noretiocholanolone could be detected in human urine after 8 months after a single injection (50 mg) nandrolone undecanoate. This time frame is narrowed to 8 days, if you take norandrostenediol 50 mg or 100 mg of norandrostenedione. We also had the opportunity to discuss this with a professional athlete who had to be tested for doping, and he gave a very high evaluation of oral steroids. He took norandrostenedione 3 grams daily, shortly before the start of the competition, and to his surprise the test results were negative.